Multiple Myeloma and Bone Resorption
A 63 years old male patient approached at our clinic for Ayurvedic treatment.
Presenting complaints - His presenting complaint was severe backache since 6 months along with pain in both legs since last 3 months and severe weakness.
History- He was pre-diagnosed as ‘Multiple myeloma’ in June 2009. He was on medicine Lenalid 10 mg (Lenalidomide by NATCO) and Dexamethasone and underwent chemotherapy thereafter in 2014.
Laboratory Reports on 6-6-2015
In the meanwhile WBC count was in the range of 2000-3500 since last 6 months.
Discussion – Multiple Myeloma is the cancer of Plasma cell. Plasma cells produce antibodies. Cancer cells accumulate in marrow and produce proteins which hamper the kidney functions.
Myeloma cells produces proteins like M proteins, Beta microglobulins which are investigated routinely in these patients along with CBC, Urine Routine, Serum calcium, uric acid for the diagnosis. Bone marrow examination is the most important test for the diagnosis.
The drug Lenalidomide is the derivative of Thalidomide and is used to treat multiple myeloma. It reduces the tumour and is used commonly in haematological conditions and in solid tumours. It has broad range of activity like it stimulates tumour apoptosis; it has anti angiogenesis and anti osteoclastogenic effects. It is very costly drug; about 9000 INR for the 30 capsules.
Ayurvedic Treatment Given-
Treatment Rationale- The drugs were selected to give symptomatic relief to the patient and to relive his obstructive pains and arrest degenerative pathology, especially in Bone Tissue.
To arrest the disease progression and to inhibit bone resorption and to inhibit the bone infiltration by neoplastic plasma cells ‘Asthiposhan’ was considered. In that perspective ‘Tikta Ksheer Basti’ periodically i.e. 7 days per month has recommended.
Results achieved - With this treatment the intensity of the pain was considerably reduced over the 2 months period.